Data/hora: 11/05/2024 12:43:41

Biblioteca(s): | Embrapa Pantanal.
Data corrente: | 25/02/2000
Data da última atualização: | 31/03/2017
Autoria: | LANUSSE, C.; LIFSCHITZ, A.; VIRKEL, G.; ALVAREZ, L.; SANCHEZ, S.; SUTRA, J. F.; GALTIER, P.; ALVINERIE, M.
Título: | Comparative plasma disposition kinetics of ivermectin, moxidectin and doramectin in cattle.
Ano de publicação: | 1997
Fonte/Imprenta: | Journal of Veterinary Pharmacology and Therapeutics, v.20, p.91-99, 1997.
Idioma: | Inglês
Conteúdo: | The persistance of the broad-spectrum antiparasitic activity of endectocide compounds relies on their disposition kinetics and pattern of plasma/tissues exchange in the host. This study evaluates the comparative plasma disposition kinetics of ivermectin (IVM), moxidectin (MXD) and doramectin (DRM) in cattle treated with commercially available injectable formulations. Twelve (12) parasite-free male Hereford calves (180-210 kg) grazing on pasture were allocated into three groups of four animals each. Animals in each group received either IVM (Ivomec 1%, MSD AGVET, Rahway, NJ, USA), MXI) (Cydectin 1%, American Cyanamid, Wayne, NJ, USA) or DRM (Dectomax 1%, Pfizer Inc., New York, USA) by subcutaneous injection at a dose of 200 ug/kg. Jugular blood samples were collected from 1 h to 80 days post-treatment, and plasma extracted, derivated and analysed by high performance liquid chromatography (HPLC) using fluorescence detection.
Thesagro: | Gado; Plasma; Sanidade Animal.
Thesaurus Nal: | cattle; doramectin; ivermectin; moxidectin.
Categoria do assunto: | --
Registro original: | Embrapa Pantanal (CPAP)
Exemplares: | CPAP - (42642-1) - ADC - SP - PP - SP16128 -  - 16128 - DIS